Code Red (3640)
Description:
A protocol for managing massive haemorrhage.
Initiation:
- Suspected active haemorrhage
- Systolic BP less than 90 (none anaesthetised patients)
- Poor responese to initial fluid resuscitation
The Blood Bank (ext 3640) must be immediately informed of a Code Red situation, and full
patient details should be made available to them.
Baseline Samples:
- Clotting Screen (Blue)
- Fibrinogen (Factor I) ()
- Full Blood Count (Purple)
- Glucose (Grey)
- Group and Save (Pink)
Send samples to Lab immediately.
Pack request:
Ask Blood Bank (ext 3640) for one
Code Red Pack 'A',
and send a Porter/Nurse to collect.
Pack A contains:
- 4 Units of Fresh Frozen Plasma
- 6 Units of Red Blood Cells
Continued bleeding:
Request 1
Code Red Pack 'B'.
Continue to request Pack 'B'
until bleeding stops.
Pack B contains:
- 2 pools of Cryoprecipitate
- 4 Units of Fresh Frozen Plasma
- 1 Unit of Platelets
- 6 Units of Red Blood Cells
(Anticipate coagulopathy.)
If bleeding persists, call Haematology SPR on bleep 6311 (or switch board, out of hours).
Cessation of bleeding:
When bleeding is under control, repeat
Full Blood Count and
clotting. Screen/administer further products if:
- Platelets less than 80 - Give 1 pool of Platelets
- Platelets less than 30 - Give 2 pools of Platelets
- Fibrinogen less than 1g/l - Give 2 pools of Cryoprecipitate
- APTT/PT ratio greater than 1.5 - Give 4 units of Fresh Frozen Plasma
Emergency Group O stocks:
Satellite fridges in St James' and Lanesborough Theatres (1st floor) each
contain 2 units of Group O negative - for extreme emergencies only.
If used, notify Blood Bank (ext 3640) immediately, so that the stocks
may be replenished.
Laboratory timings:
Blood Grouping and Cross Matching
With a correctly labelled sample, a blood group can be identified within 10 minutes, so
that group specific blood may be issued. An antibody screen takes approximately 40 minutes.
Fresh Frozen Plasma
FFP has to be defrosted before issue, and takes approximately 30 minutes.
Each dose of FFP contains 15 ml/kg. The average adult requires 4 units.
Cryoprecipitate
Cryoprecipitate takes approximately 30 minutes to defrost. For the average adult, a dose
should contain 2 pools.
Platelets
Platelets are not stocked in the Blood Bank (ext 3640), and must be
obtained from the
National Blood Service (hospital bank).
Issuance takes 30-40 minutes.
Note:
- There should be no delay in administering Platelets.
- Platelets should NEVER be refrigerated.
Useful numbers:
Centre | Number |
Blood Bank | Extension 3640 |
Haematology SPR | Bleep 6311 |
Definitions
Full Blood Count:
The Full Blood (or Complete) Count, using a sample or peripheral blood, provides information
about the type, number and appearance of red blood cells, white blood cells, and platelets.
The test can indicate anaemia, infection, and blood disorders.
Group & save:
1. To determine the ABO and Rhesus type.
2. To detect red cell antibodies, plus anti A or anti B which could haemolyse
transfused red cells.
3. Save the serum for 7 days, for further type testing, if blood is needed later.
Group and Save does not allow blood to be immediately available, and is used when a
need to transfuse is possible, but not expected. The Group and Save test is easy and quick
to perform, and does not remove blood from the common pool.
Cross matching:
- Determines the patient's ABO and Rhesus D type
- Detects red cell antibodies which could haemolyse transfused red cells
- Confirms compatibility with each of the units of red cells to be transfused
Cross match means to fully type a sample and a unit of donated blood (from a common pool),
to look for cross reaction. It takes up to an hour to perform, but makes blood available
for immediate use.
Clotting Screen:
A clotting Screen provides a baseline
assay of the blood's
coagulation ability. The test comprises:
- Platelet count
- Time it takes for Platelets to function
- Prothrombin ratio
- Activated Partial Thromboplastin time
- Fibrinogen assay
- Blood count
- Liver function - to exclude liver disease as a reason for coagulation problem
Fibrinogen (Factor I):
Fibrinogen is a soluble plasma glycoprotein, synthesised by the liver, which is converted by
thrombin into fibrin during blood coagulation. Fibrin is cross linked, by factor XIII, to form a clot.